In the Apg3 classification Scrophulariaceae is a Family in Lamiales. A big part of Scrophulariaceae as defined in the Cronquist system was shown to be polyphyletic and has been transferred to other Families like Calceolariaceae, Orobanchacea, Plantaginaceae, Phrymaceae and Stilbaceae. To make Scrophulariaceae monophyletic other Families had to be included: Buddlejaceae, Myoporaceae and Selaginaceae.
In the Plant theory Verbenales is split off from Lamiales. Scrophulariaceae is in Subphase 4 in Lamiales.